Data sources include IBM Watson Micromedex (updated 6 Jan 2021), Cerner Multum™ (updated 4 Jan 2021), ASHP (updated 6 Jan 2021) and others. View abstract. Guar gum in a weight-loss product was implicated as causing esophageal obstruction in a patient who exceeded the recommended dosage.59 In a review, 18 cases of esophageal obstruction, 7 cases of small bowel obstruction, and possibly 1 death were associated with the use of Cal-Ban 3000, a guar gum–containing diet pill.60 The water-retaining capacity of the gum can cause it to swell 10- to 20-fold and may lead to luminal obstruction, particularly when an anatomic predisposition exists. McIvor, M. E., Cummings, C. C., Van Duyn, M. A., Leo, T. A., Margolis, S., Behall, K. M., Michnowski, J. E., and Mendeloff, A. I. Guar gum has been used for centuries as a thickening agent for foods and medicines. Guar beans have a large endosperm that contains galactomannan gum, a substance which forms a gel in water. Fuessl, H. S., Williams, G., Adrian, T. E., and Bloom, S. R. Guar sprinkled on food: effect on glycaemic control, plasma lipids and gut hormones in non-insulin dependent diabetic patients. View abstract. The influence of Guar gum on absorption of metformin from the gut in healthy volunteers. Diabetologia 1981;20(6):612-5. Guar gum: processing, properties and food applications- a review. Br.J.Nutr. One small study of 10 elderly subjects showed a reduction in postprandial hypotension (PPH) (defined as a decrease in systolic blood pressure greater than 20 mm Hg occurring within 2 hours of the end of a meal).49 These data were corroborated in a double-blind, randomized, placebo-controlled, crossover trial in 22 older women in South Korean community senior centers in which significant differences in postprandial systolic blood pressure were noted between the guar gum (9 g pre-meal intervention) and control groups with the greatest difference (18.2 mm Hg; P = 0.004) observed at 45 minutes after eating. Uses of Guar Gum in Food. A multicenter randomized open trial. Sadhukhan, B., Roychowdhury, U., Banerjee, P., and Sen, S. Clinical evaluation of a herbal antidiabetic product. View abstract. View abstract. J.Gerontol.A Biol.Sci.Med.Sci. 1990;270:7-16. Reduced or blocked flow of bile from the liver (cholestasis). Thyroid hormone use and bone mineral density in elderly men. View abstract. Eur J Obstet Gynecol Reprod Biol 1996;67(2):109-113. 2002;56(8):771-778. Maintenance therapy with partially hydrolyzed guar gum in the conservative treatment of chronic anal fissure: results of a prospective, randomized study. View abstract. Beattie, V. A., Edwards, C. A., Hosker, J. P., Cullen, D. R., Ward, J. D., and Read, N. W. Does adding fibre to a low energy, high carbohydrate, low fat diet confer any benefit to the management of newly diagnosed overweight type II diabetics? Taking guar gum by mouth might reduce stomach pain and improve bowel function and quality of life in people with IBS. Jensen CD, Spiller GA, Gates JE, et al. Experiences with three different fiber supplements in weight reduction. Long term effects of guar gum on lipid metabolism after carotid endarterectomy. J Am Diet Assoc 1998;98:912-4. The viscosity of these gels is generally unaffected by the pH of the solution. Lancet 5-17-1975;1(7916):1116-1117. 1980;208(1-2):45-48. Diabet.Med. View abstract. Therefore guar gum is a valuable additive for pet foods. Fructosamine levels were lower after treatment with guar gum compared with the end of placebo period 1; however, upon stopping guar gum, the fructosamine level began to increase as noted in placebo period 2. Drugs 1990;39:917-28.. View abstract. J.Am.Geriatr.Soc. View abstract. View abstract. Soluble fiber reduces the incidence of diarrhea in septic patients receiving total enteral nutrition: a prospective, double-blind, randomized, and controlled trial. This is only a brief summary of general information about this product. View abstract. Nicastri P. L., Diaferia A., Tartagni M., Loizzi P., Fanelli M. A randomised placebo-controlled trial of ursodeoxycholic acid and S-adenosylmethionine in the treatment of intrahepatic cholestasis of pregnancy. Int.J.Obes.Relat Metab Disord. Am J Prev Med 1999;17:18-23. Pittler MH, Ernst E. Guar gum for body weight reduction: Meta-analysis of randomized trials. Diabetes Res.Clin.Pract. Cicero, A. F., Derosa, G., Manca, M., Bove, M., Borghi, C., and Gaddi, A. V. Different effect of psyllium and guar dietary supplementation on blood pressure control in hypertensive overweight patients: a six-month, randomized clinical trial. This information should not be used to decide whether or not to take this product. Small tears in the lining of the anus (anal fissures). Stool consistency and abdominal pain in irritable bowel syndrome may be improved by partially hydrolysed guar gum. Takahashi H, Wako N, Okubo T, et al. Guar gum can decrease how much ethinyl estradiol the body absorbs. Guar gum can decrease how much metformin the body absorbs. View abstract. View abstract. J.Pediatr.Gastroenterol.Nutr. Am J Cardiol. 2001;25(3):307-315. View abstract. 1981;34(11):2446-2449. Acta Biomed.Ateneo.Parmense. Ned.Tijdschr.Geneeskd. Guar gum is a food additive/thickener. Chuang LM, Jou TS, Yang WS, et al. Alam, N. H., Ashraf, H., Sarker, S. A., Olesen, M., Troup, J., Salam, M. A., Gyr, N., and Meier, R. Efficacy of partially hydrolyzed guar gum-added oral rehydration solution in the treatment of severe cholera in adults. A., Lai, C. S., Corwin, H., Ma, Y., Maki, K. C., Garleb, K. A., and Wolf, B. W. Inclusion of guar gum and alginate into a crispy bar improves postprandial glycemia in humans. In manufacturing, guar gum is used as a binding agent in tablets, and as a thickening agent in lotions and creams.