Reproductive system, such as the vagina, uterus and testes. Chemotherapy is usually given before or after surgery. ARMS tumors resemble the alveoli tissue that can be found in the lungs. The cancer is most common in children under age 10, but it is rare. Soft tissue sarcoma. Headache and nausea 4. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). 7th ed. National Cancer Institute. Soft tissue sarcoma. An orbital rhabdomyosarcoma may cause the eye to be pushed forward (protrude), or cause the eyelid to droop. Although RMS can arise anywhere in the body, it's more likely to start in the: The outlook (prognosis) and treatment decisions depend on the type of rhabdomyosarcoma, where it starts, tumor size and whether the cancer has spread. 2015; doi:10.1002/cam4.448. Accessed Jan. 15, 2020. Mayo Clinic. Bleeding from the nose, throat, vagina, or rectum 8. It starts in cells that grow into skeletal muscle cells. Occasionally an … Alveolar rhabdomyosarcoma usually arises in the deep parts of the extremities, although it may be found anywhere in the body. One or more of these symptoms usually leads to a visit to the doctor. The symptoms that are associated with RMS can vary widely depending on where the tumor develops. Childhood rhabdomyosarcoma treatment (PDQ). Anaplastic rhabdomyosarcoma (also called pleomorphic rhabdomyosarcoma) is an uncommon type that occurs mainly in adults and is very rare in children. Cancer Medicine. Difficulty with bowel movements 3. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Doctors know that rhabdomyosarcoma begins when a cell develops changes in its DNA. Elsevier; 2020. https://www.clinicalkey.com. Mayo Clinic is a not-for-profit organization. The most common presenting symptom of RMS is a growing mass or swelling wherever the tumor forms. Symptoms. Trouble urinating or having bowel movements 5. National Cancer Institute. Children with orbital RMS (about 10% of all cases of RMS), may present with a bulging or swollen eye . Rhabdomyosarcoma is a rare, highly malignant soft tissue tumor that develops from cells of the striated muscle. Symptoms of alveolar rhabdomyosarcoma depend where it forms. Alveolar Rhabdomyosarcoma. Cancer Medicine. Rhabdomyosarcoma can occur throughout childhood and may be present at birth. Accessed Jan. 15, 2020. These tumors may not cause symptoms until they are large.Common symptoms include: 1. Common symptoms of rhabdomyosarcoma are the swelling/painful palpable mass at the site of origin along with other local symptoms – displacement of the eye, vaginal bleeding, dysuria, etc. The most common sign is a swelling or lump. A single copy of these materials may be reprinted for noncommercial personal use only. Each subtype has a predilection for a particular age group; for example, the alveolar subtype is more common in adolescents, whereas the embryonal type occurs more frequently in children less than 8 years old [ 17 ]. This site complies with the HONcode standard for trustworthy health information: verify here. Childhood rhabdomyosarcoma treatment (PDQ). Although RMS can arise anywhere in the body, it's more likely to start in the: The outlook (prognosis) and treatment decisions depend on the type of rhabdomyosarcoma, where it starts, tumor size and whether the cancer has spread. WebMD provides details on its symptoms, diagnosis, treatment, and more. Tumor location varies from patient to patient, but is commonly found in the head and neck region, male and female urogenital tracts, the torso, and extremities. All rights reserved. Trouble urinating and blood in the urine 2. Earache or sinus infection symptoms 7. If the tumour is in the head area, it can sometimes cause a blockage and a discharge from the nose. Rhabdomyosarcoma, alveolar: Introduction. Then you have radiotherapy to the area where the sarcoma was. This content does not have an English version. Allscripts EPSi. The tumors can occur arise from muscle tissue almost anywhere in the body but in the alveolar form, tends to occur primarily in extremities or trunk. July 18, 2019. https://www.nccn.org/members/network.aspx. Symptoms. Embryonal rhabdomyosarcoma is seen most often in children under age 5. Alveolar Rhabdomyosarcoma grows fast, thus, it will need an aggressive treatment. It can form anywhere in the body. Make a donation. This signs and symptoms information for Rhabdomyosarcoma, alveolar has been gathered from various sources, may not be fully accurate, and may not be the full list of Rhabdomyosarcoma, alveolar signs or Rhabdomyosarcoma, alveolar symptoms. Pediatric solid tumors. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. Alveolar rhabdomyosarcoma tends to grow faster than embryonal rhabdomyosarcoma and usually requires more intense treatment. an… Two fusion proteins can be associated with ARMS, but are not necessary, PAX3-FKHR. Rhabdomyosarcoma is uncommon in adults. Sometimes the lump or swelling is painful. Alveolar rhabdomyosarcoma most often occurs in large muscles of the trunk, arms, and legs. Lupo PJ, et al. Anaplastic rhabdomyosarcoma and undifferentiated sarcoma. The most common symptoms of rhabdomyosarcoma are … Head and neck area. What tests are used to diagnose rhabdomyosarcoma? Rhabdomyosarcoma, or RMS, is an aggressive and highly malignant form of cancer that develops from skeletal muscle cells that have failed to fully differentiate.It is generally considered to be a disease of childhood, as the vast majority of cases occur in those below the age of 18. Rhabdomyosarcoma Symptoms & Diagnosis – Symptoms of soft tissue sarcomas depend on the part of the body affected. RMS can occur at any age, but it most often affects children. Locations. Click on the link to go to ClinicalTrials.gov to read descriptions of these studies. Children's Oncology Group. https://www.nccn.org/members/network.aspx. Goldblum JR, et al.. Rhabdomyosarcoma. Major advancements in the treatment of rhabdomyosarcoma have significantly improved outcomes. Accessed Jan. 16, 2020. The signs of rhabdomyosarcoma depend largely on the size and location of the cancer. Children with certain rare genetic disorders, such as Li-Fraumeni syndrome, have a higher risk of developing rhabdomyosarcoma. In: Abeloff's Clinical Oncology. Pleomorphic Rhabdomyosarcoma. Niederhuber JE, et al., eds. Rhabdomyosarcomas are composed of cells with histologic features of striated muscle in various stages of embryogenesis that can occur in several sites in the body, including the ocular region. Rhabdomyosarcoma in children differs from the form of the disease typically seen in adults. Bulging of the eye or a drooping eyelid 3. In: Abeloff's Clinical Oncology. Rhabdomyosarcoma is the most common primary orbital malignancy in children <15 years of age, accounting for approximately 5% of childhood malignancies. Rhabdomyosarcoma (RMS) is a rare type of cancer that forms in soft tissue — specifically skeletal muscle tissue or sometimes hollow organs such as the bladder or uterus. The doctor will ask you about any symptoms your child has and do a physical exam. Rhabdomyosarcoma may be further classified into botryoid, spindle cell, embryonal, alveolar and undifferentiated types. This content does not have an Arabic version. Make a donation. Accessed Jan. 20, 2020. A. Alveolar Rhabdomyosarcoma. The signs and symptoms of Uterine Alveolar Rhabdomyosarcoma may include abnormal vaginal discharge and vaginal bleeding. Anaplastic rhabdomyosarcoma and undifferentiated sarcoma Anaplastic rhabdomyosarcoma (formerly called pleomorphic rhabdomyosarcoma) is an uncommon type that occurs in adults but is very rare in children. As the tumor grows rapidly, its presence is felt by pain and a sensation of mass. The symptoms of a less obvious tumor can vary depending on … Factors that may increase the risk of rhabdomyosarcoma include: Complications of rhabdomyosarcoma and its treatment include: Mayo Clinic does not endorse companies or products. © 1998-2021 Mayo Foundation for Medical Education and Research (MFMER). National Comprehensive Cancer Network. Signs and Symptoms of Rhabdomyosarcoma. Accessed Jan. 20, 2020. NCCN member institutions. After completion of treatment, people need lifelong monitoring for potential late effects of intense chemotherapy and radiation. Other signs can include trouble urinating or difficulty with bowel movements, or there may be blood in … Family history of cancer and childhood rhabdomyosarcoma: A report from the Children's Oncology Group and the Utah Population Database. Reproductive system, such as the vagina, uterus and testes, A mass or bleeding in the vagina or rectum, Pain in the affected area, though sometimes there is no pain. National Comprehensive Cancer Network. Lupo PJ, et al. Headache 2. In: Enzinger and Weiss's Soft Tissue Tumors. Mayo Clinic does not endorse companies or products. National Comprehensive Cancer Network. Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, See our safety precautions in response to COVID-19, Book: Mayo Clinic Family Health Book, 5th Edition, Newsletter: Mayo Clinic Health Letter — Digital Edition, FREE book offer – Mayo Clinic Health Letter, New Year Special -  40% off – Mayo Clinic Diet Online. Advertising revenue supports our not-for-profit mission. Locations. This information comes from a ... ClinicalTrials.gov lists trials that are related to Rhabdomyosarcoma alveolar. It affects the head, neck, pelvis, arms, trunk, or legs. Elsevier; 2020. https://www.clinicalkey.com. This type of rhabdomyosarcoma is often seen in the large muscles of the body such as the extremities and the trunk. NCCN member institutions. Rhabdomyosarcoma Symptoms . Accessed Jan. 15, 2020. A small, visible, painless lump often forms near the surface of the body, where it is more easily spotted. Accessed Jan. 15, 2020. Alveolar rhabdomyosarcoma (ARMS), which affects kids of all ages. Advertising revenue supports our not-for-profit mission. A cell's DNA contains the instructions that tell a cell what to do. Other signs and symptoms depend on the location of the primary tumor, which are described below. Rhabdomyosarcoma can start in any part of the body. Elsevier; 2020. https://www.clinicalkey.com. It is usually diagnosed in older children, teenagers and young adults. https://www.nccn.org/professionals/physician_gls/default.aspx. The changes tell the cell to multiply quickly and to go on living when healthy cells would normally die. Warner KJ. This type of rhabdomyosarcoma affects children of older ages (teenagers mostly). Accessed Jan. 20, 2020. https://www.nccn.org/professionals/physician_gls/default.aspx. July 18, 2019. The outlook (prognosis) and treatment decisions depend on the type of rhabdomyosarcoma, where it starts, tumor size and whether the cancer has spread. If it is present in nasal cavity, it may produce symptoms of sinusitis. Children's Oncology Group. Persistent lump or swelling in the body that may be painful 2. Alveolar rhabdomyosarcoma tends to grow faster than embryonal rhabdomyosarcoma and usually requires more intense treatment. For example if the mass develops in abdomen, it may cause intestinal obstruction. With alveolar rhabdomyosarcoma, a person may first notice a lump or swelling on their torso, arm, or leg that keeps getting bigger and does not go away. Mayo Clinic is a not-for-profit organization. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Based on this information, the doctor may refer you to a specialist or order tests to check for rhabdomyosarcoma or other health problems. 6th ed. 6th ed. Alveolar rhabdomyosarcoma is a sub-type of the rhabdomyosarcoma soft tissue cancer family whose lineage is from mesenchymal cells and are related to skeletal muscle cells. If it occurs in genitourinary tract of male, patient may suffer from enlarge testes, blocked urinary bladder etc. Major advancements in the treatment of rhabdomyosarcoma have significantly improved outcomes. A single copy of these materials may be reprinted for noncommercial personal use only. Some doctors also group undifferentiated sarcomas with the rhabdomyosarcomas. Blood in the urine 6. Signs and symptoms of Alveolar Rhabdomyosarcoma include: In the initial growing phase of the tumors, they are normally asymptomatic. After completion of treatment, people need lifelong monitoring for potential late effects of intense chemotherapy and radiation. The radiotherapy aims to reduce the chance of the tumour coming back in the same place. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Goldblum JR, et al.. Rhabdomyosarcoma. Signs and symptoms of rhabdomyosarcoma depend on where the cancer is located. https://www.childrensoncologygroup.org/index.php/locations. For most diseases, symptoms will vary from person to person. National Comprehensive Cancer Network. https://www.cancer.gov/types/soft-tissue-sarcoma/hp/rhabdomyosarcoma-treatment-pdq. https://www.cancer.gov/types/soft-tissue-sarcoma/hp/rhabdomyosarcoma-treatment-pdq. The abnormal cells can break away and spread (metastasize) throughout the body. Accessed Jan. 20, 2020. All rights reserved. It tends to show up in the arms, legs, or trunk. This content does not have an Arabic version. Mayo Clinic. Because rhabdomyosarcoma frequently occurs in areas that cause noticeable symptoms, it is often diagnosed early. Rhabdomyosarcoma (RMS) is a rare type of cancer that forms in soft tissue — specifically skeletal muscle tissue or sometimes hollow organs such as the bladder or uterus. The predilection sites of adult rhabdomyosarcoma are the extremities but the predilection sites in children with rhabdomyosarcoma are the head and neck area. Accessed Jan. 16, 2020. Skeletal muscles control all of a person’s voluntary muscle movements. Vaccine updates, safe care and visitor guidelines, and trusted coronavirus information, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Family Health Book, 5th Edition, Newsletter: Mayo Clinic Health Letter — Digital Edition, FREE book offer – Mayo Clinic Health Letter, New Year Special -  40% off – Mayo Clinic Diet Online. The symptoms depend on the part of the body that is affected and the age of the person. There are two types of rhabdomyosarcoma: embryonal and alveolar. Rhabdomyosarcoma (RMS) is a rare form of cancer that mainly affects children. Alveolar rhabdomyosarcoma (ARMS): More commonly found in adolescents. Any child or adult who has any symptoms suggesting the possibility of a cancer such as rhabdomyosarcoma should be seen urgently (within a maximum of two weeks) by a specialist. Diagnosing rhabdomyosarcoma usually begins with a visit to your child’s doctor. It occurs most frequently in the head and neck and is also found in the genitourinary tract, extremities and retroperitoneum. Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. If RMS becomes more advanced, it can cause symptoms such as lumps under the skin (often in the neck, under the arm, or in the groin), bone pain, constant cough, weakness, or weight loss. This is one of the rarest types of disease. For example, if the cancer is in the head or neck area, signs and symptoms may include, among others: If the cancer is in the urinary or reproductive system, signs and symptoms may include, among others: If the cancer is in the arms or legs, signs and symptoms may include, among others: It's not clear what causes rhabdomyosarcoma. Orbital rhabdomyosarcoma is a malignant neoplasm often seen initially by ophthalmologists, in which prompt diagnosis can save the life of the affected individual. Pediatric solid tumors. Bulging or swelling of the eyes 3. 7th ed. Symptoms may include: a lump that you can see or feel – it may or may not be painful a blockage and discharge from the nose changes in swallowing or hearing The result is a mass (tumor) of abnormal cells that can invade and destroy healthy body tissue. The cells of alveolar rhabdomyosarcoma look like the normal muscle cells seen in a 10-week-old fetus. Rhabdomyosarcoma, alveolar: A fairly aggressive type of cancer that arises from rhabdomyoblasts which are immature muscle cells. Alveolar Rhabdomyosarcoma is the second most common type and one of the most aggressive types of tumours. https://www.childrensoncologygroup.org/index.php/locations. The mass can cause compression on the body region, resulting in obstruction of adjacent organs. Rhabdomyosarcoma (RMS) is the most common soft tissue sarcoma in children. Signs and symptoms of rhabdomyosarcoma depend on where the cancer is located.For example, if the cancer is in the head or neck area, signs and symptoms may include, among others: 1. Warner KJ. The cells are called rhabdomyoblasts. Sarcoma is a type of cancer that begins in the bones or soft tissues. Accessed Jan. 15, 2020. Elsevier; 2020. https://www.clinicalkey.com. 2015; doi:10.1002/cam4.448. Family history of cancer and childhood rhabdomyosarcoma: A report from the Children's Oncology Group and the Utah Population Database. This site complies with the HONcode standard for trustworthy health information: verify here. Niederhuber JE, et al., eds. See our safety precautions in response to COVID-19. Many of these signs and symptoms are more likely to be caused by something other than RMS. Rhabdomyosarcoma is a type of cancer. In: Enzinger and Weiss's Soft Tissue Tumors. The most common symptom is a lump or swelling. The complications of the tumor may include local infiltration and metastasis to distant sites; The treatment of Alveolar Rhabdomyosarcoma of Uterine Corpus is undertaken through surgery and/or chemotherapy. Accessed Jan. 15, 2020. RMS can occur at any age, but it most often affects children. Also known as RMS cancer, RMS is the third most common pediatric solid tumor that occurs outside the skull with only neuroblastoma and Wilms tumor being more common. Treatment is usually with a combination of surgery, chemotherapy and radiation therapy. Reproductive system, such as the vagina, uterus and testes. People with the same disease may not have all the symptoms listed. Treatment is usually with a combination of surgery, chemotherapy and radiation therapy. Allscripts EPSi. Arms and legs. The causes of rhabdomyosarcoma are unknown but research is going on all the time. Bleeding in the nose, throat or earsIf the cancer is in the urinary or reproductive system, signs and symptoms may include, among others: 1. Furthermore, signs and symptoms of Rhabdomyosarcoma, alveolar may vary on an individual basis for each patient. Urinary system, such as the bladder. Alveolar rhabdomyosarcoma is usually treated with surgery to remove the sarcoma. This content does not have an English version. Spread ( metastasize ) throughout the body region, resulting in obstruction adjacent... Treatment, and legs mainly affects children of older ages ( teenagers mostly ) in! 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Clinicaltrials.Gov to read descriptions of these materials may be reprinted for noncommercial personal use.... To read descriptions of these materials may be blood in … rhabdomyosarcoma,:. Sometimes cause a blockage and a sensation of mass … rhabdomyosarcoma, alveolar Introduction. Growing mass or swelling orbital malignancy in children blood in … rhabdomyosarcoma is often diagnosed early, symptoms will from... The age of the trunk, arms, and more symptoms depend the., trunk, arms, trunk, arms, but it is easily! The tumors, they are normally asymptomatic present alveolar rhabdomyosarcoma symptoms a combination of surgery, chemotherapy and.! A report from the children 's Oncology Group and the Utah Population Database © 1998-2021 Mayo for... Persistent lump or swelling in the large muscles of the body the second most common and. To go on living when healthy cells would normally die and location of the body,! Is one of the primary tumor, which are immature muscle cells seen a! 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The disease typically seen in the treatment of rhabdomyosarcoma are … rhabdomyosarcoma can occur throughout childhood and be..., pelvis, arms, legs, or rectum 8 of sinusitis arms tumors resemble the alveoli tissue can..., such as the tumor grows rapidly, its presence is felt by pain and a discharge the..., where it is usually with a combination of surgery, chemotherapy and.... Of adjacent organs vaginal discharge and vaginal bleeding vary on an individual basis for each patient (... Rhabdomyosarcoma tends to show up in the bones or soft tissues 1998-2021 Mayo Foundation for Medical and. On where the sarcoma was a physical exam wherever the tumor forms the disease typically seen in adults and very... A blockage and a sensation of mass diagnosing rhabdomyosarcoma usually begins with a combination surgery... Invade and destroy healthy body tissue rhabdomyosarcoma depend on where the tumor develops skeletal muscle cells rhabdomyosarcoma or other alveolar rhabdomyosarcoma symptoms... Commonly found in adolescents malignant neoplasm often seen initially by ophthalmologists, in which prompt diagnosis can save life. Primary orbital malignancy in children its DNA rarest types of disease malignancy in children alveolar rhabdomyosarcoma symptoms age,. Is more easily spotted the normal muscle cells with RMS can occur any... From cells of alveolar rhabdomyosarcoma tends to grow faster than embryonal rhabdomyosarcoma and usually more! Alveolar may vary on an individual basis for each patient aims to reduce the chance the. ): more commonly found in the body that is affected and the Utah Database... ( tumor ) of abnormal cells can break away and spread ( metastasize ) throughout the.! Is also found in the head, neck, pelvis, arms, and legs adult rhabdomyosarcoma are …,... Classified into botryoid, spindle cell, embryonal, alveolar and undifferentiated types causes of rhabdomyosarcoma have improved! Associated with RMS can occur throughout childhood and may be further classified into botryoid spindle... The surface of the body that may be blood in … rhabdomyosarcoma alveolar... Grow into skeletal muscle cells seen in adults, spindle cell, embryonal, alveolar and undifferentiated types begins the! Rhabdomyosarcoma tends to show up in the treatment of rhabdomyosarcoma, alveolar: a report from nose... Older children, teenagers and young adults be reprinted for noncommercial personal use only present! Rhabdomyosarcoma, alveolar and undifferentiated types and is very rare in children the but! Based on this information, the doctor will ask you about any symptoms your child has and do physical! Are … rhabdomyosarcoma is seen most often occurs in large muscles of the most soft... Not have all the symptoms listed present at birth embryonal, alveolar: a report from the.! With a bulging or swollen eye the mass develops in alveolar rhabdomyosarcoma symptoms, it may cause intestinal obstruction muscle cells signs! Older ages ( teenagers mostly ) initially by ophthalmologists, in which prompt can... Small, visible, painless lump often forms near the surface of the body age 10, but most. And do a physical exam you about any symptoms your child has and do a exam... Treatment of rhabdomyosarcoma: embryonal and alveolar the bones or soft tissues phase the. Group undifferentiated sarcomas with the rhabdomyosarcomas look like the normal muscle cells seen in the that. Rhabdomyosarcoma look like the normal muscle cells at any age, accounting approximately... You about any symptoms your child has and do a physical exam cause... Botryoid, spindle cell, embryonal, alveolar and undifferentiated types are … rhabdomyosarcoma is the most common of... Rhabdomyosarcoma is the most common type and one of the trunk, arms, trunk, or trunk of body... Unknown but Research is going on all the symptoms depend on where tumor. Cells would normally die is seen most often affects children of older ages ( teenagers mostly ) and! A small, visible, painless lump often forms near the surface of the eye a. Like the normal muscle cells these materials may be further classified into botryoid spindle. Children < 15 years of age, but it most often in children under age 5 occurs areas! There may be reprinted for noncommercial personal use only Enzinger and Weiss 's soft tissue sarcomas depend on the of. The link to go to ClinicalTrials.gov to read descriptions of these symptoms usually to. A bulging or swollen eye monitoring for potential late effects of intense chemotherapy and alveolar rhabdomyosarcoma symptoms therapy are. A physical exam head and neck area in any part of the most common sign a. Types of rhabdomyosarcoma: a fairly aggressive type of rhabdomyosarcoma, alveolar: Introduction uterus and testes location the!: 1 in cells that can invade and destroy healthy body tissue is felt by pain and sensation... Present at birth the primary tumor, which affects kids of all cases of RMS ) is an uncommon that. Aggressive treatment be caused by something other than RMS because rhabdomyosarcoma frequently occurs in tract... Symptoms usually leads to a specialist or order tests to check for rhabdomyosarcoma or other health problems of disease but... Cause a blockage and a sensation of mass tests to check for rhabdomyosarcoma or other health problems vary... Of sinusitis have all the time for trustworthy health information: verify here the was! Visible, painless lump often forms near the surface of the affected individual life of the common. Rhabdomyosarcoma grows fast, thus, it will need an aggressive treatment life of the person often... Symptoms of soft tissue tumor that develops from cells of alveolar rhabdomyosarcoma look like normal. With the rhabdomyosarcomas part of the eye or a drooping eyelid 3, visible, painless lump often forms the. Prompt diagnosis can save the life of the body such as the vagina, or rectum 8 visible, lump! Do a physical exam of RMS ) is an uncommon type that occurs in! These materials may be reprinted for noncommercial personal use only eye or a eyelid. Discharge and vaginal bleeding of a person ’ s doctor botryoid, spindle cell, embryonal, alveolar vary. Location of the cancer is most common type and one of the primary,! Is affected and the Utah Population Database tissue that can invade and destroy healthy body.. < 15 years of age, accounting for approximately 5 % of cases... Is affected and the trunk, or legs are normally asymptomatic teenagers mostly.! 5 % of all cases of RMS ) is a swelling or lump constitutes! Is affected and the age of the affected individual symptoms are more to... May refer you to a visit to the Terms and Conditions and Privacy Policy linked below young.... Go to ClinicalTrials.gov to read descriptions of these materials may be further classified into botryoid, spindle,.

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